The first bath should be between hours 2 and 4 after birth in order to stabilize the body temperature of the baby to minimize the risk of hypothermia, and the ambient temperature should be controlled after batch. The bath should be postponed to later than hour 24 particularly for babies younger than 36 weeks. Daily bath is not recommended. Bathing twice a week is recommended for term babies and bathing with 4 days intervals is recommended for preterm babies. Opinions on the ideal bath water temperature vary: Close to body temperature (37-37.5°C) or low temperature (34-36°C) is recommended. The bathing time should be short (<5 minutes). For skin cleaning, non-alkali soft formula, neutral or slightly acidic, odor-free, liquid syndets should be preferred. Rubbing should be avoided. Skin curves should be dried carefully after bathing. For premature babies without a risk of infection, cleaning 2-3 times a week with warm, sterile water is recommended for the first few weeks of their lives. There is not a standard pediatric formula for baby shampoos. Use of shampoos which contain amphoteric and non-ionic agents is not absolutely necessary for newborns with short, thin and fragile hair strands. Shampoos with a soft formula, and a pH value close to tear (tear-free) should be preferred. Sodium lauryl sulfate (SLS) in shampoos is among the leading substances which should be avoided in topical application to the newborn. SLS; damages the lipid barrier, and causes irritation which leads to separation between skin layers. SLS remains attached to the skin for days when applied with triclosan. Sodium and ammonium laurate sulfate is added in cleaning care products to create a foaming effect. Newborn products should not contain these agents as they produce an irritating effect with protein damage. Methylisothiazolinone is included in hair care products, and reportedly, it may be absorbed and cause neurological disorders. Parabens are present in (methyl paraben, propyl paraben, ethyl paraben, butyl paraben) baby shampoo and lotions and wipes; it should be noted that they could cause contact dermatitis.